[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] Research Institute Brainclinics: Applied Neuroscience, Neuromodulation and Personalized Medicine for ADHD and Depression. Brainclinics was established in 2001 as a research institute specialized in Applied Neuroscience, Neuromodulation, and Personalized Medicine with a focus on ADHD and depression. More scientific backgrounds on Neurofeedback in ADHD and rTMS in depression can be found here. For more client related information on these topics also see the neuroCare Clinics website Brainclinics conducts applied brain research (Applied Neuroscience) using of techniques such as EEG and QEEG, Actigraphy, Event Related Potentials (ERPs) and neuropsychological assessments. iSPOT study of ADHD and Depression Currently Research...
ADHD: Symptoms, Causes and Treatment
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] ADHD: Symptoms, Causes and Treatment ADHD stands for Attention Deficit Hyperactivity Disorder. ADHD often distinguishes ADHD with hyperactivity (ADHD) and without hyperactivity (ADD). What is ADHD? ADHD symptoms causes treatment In the seventies, scientists began to use the term attention deficit (hyperactivity) disorder, ADHD, to describe the symptoms (see below). Although most complaints are often related to children, it is known that symptoms such as lack of concentration, impulsivity and overactivity persist into adulthood. Relatively few of these adults are diagnosed or treated as such. They can still benefit from medication (such as Ritalin, Concerta or Strattera) and...
EEG Examples: Beta spindles and low voltage
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] EEG Examples: Beta spindles and Low Voltage EEG Beta spindles Family studies have shown that frontal and fronto-central beta spindles and excess beta exhibit an autosomal dominant mode of inheritance in healthy persons, but these patterns can also occur as a result of brain damage. Furthermore, the pattern of fronto-precentral beta has a lower frequency in Japanese (Vogel, 1970). A strong linkage between beta frequencies and GABA-A receptor genes has been reported, in line with the often-reported medication effects of benzodiazepines resulting in a ‘beta buzz’ (Porjesz et al., 2002). Spindling Excessive Beta or Beta Spindles are...
Alpha Peak Frequency
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] Individual Alpha Peak Frequency (iAPF) As pointed out in the section on ADHD, ADHD patients with a slow iAPF were found to be non-responders to stimulant medication. Furthermore, it was demonstrated that there was a clear relationship between the iAPF at baseline and subsequent improvement in comorbid depressive symptoms as a result of neurofeedback. Arns et al. (2010, 2011) provided further evidence that this measure is a clear predictor for non-response to rTMS treatment in depression, whereas other studies have also found that a slow iAPF is related to unfavorable treatment outcome to rTMS (Conca et al.,...
ADHD History: EEG and QEEG findings
[vc_row][vc_column][vc_column_text el_class="maintext"] [WP-Coder id="1"]History of Neurophysiological findings in ADHD ADHD History: EEG QEEG Attention-Deficit/Hyperactivity Disorder (ADHD) has become one of the most common neurodevelopmental and psychiatric disorders of childhood. The general rate of prevalence is reported between 3% to 7% of school age children (Cormier, 2008). In 40-60% of all cases ADHD persists in adolescence and adulthood (Faraone, Biederman & Mick, 2006). Currently, the disorder is primarily diagnosed by referring to the criteria of the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition Text Revision (DSM-IV, 1994) or the International Statistical Classification of Mental Disorders (ICD-10, World Health Organization, 1992)....
neurofeedback evidence based treatment for adhd
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] New research shows: Neurofeedback is an ‘Evidence-Based’ treatment for ADHD. Nijmegen, July 16th 2009 – Neurofeedback – also called EEG Biofeedback – is a method used to train brain activity in order to normalize Brain function and treat psychiatric disorders. This treatment method has gained interest over the last 10 years, however the question whether this treatment should be regarded as an Evidence-Based treatment was unanswered until now. Tomorrow a study will be published in the scientific journal ‘Clinical EEG and Neuroscience’ demonstrating that Neurofeedback can indeed be regarded as an evidence-based treatment for Attention Deficit- /...
History of the EEG and QEEG
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] history of the EEG and QEEG History: From EEG to Quantitative EEG (QEEG) In 1929 Hans Berger reported in an publication his observations on what he termed ‘das Elektrenkephalogramm’ (Berger, 1929), which would become the seminal paper highlighting the beginning of research on the human electroencephalogram also abbreviated as EEG. In his first experiments he recorded the EEG from his son Klaus – among others – and described extensively the methods he used and what he observed. Figure 1 below demonstrates 2 graphs from that first publication recorded from his son. The bottom figure represents the rhythm...
Depression history of EEG and QEEG findings
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] History of neurophysiological findings in depression Depression history of EEG and QEEG findings Major depression is a common disorder with millions of sufferers around the world and a lifetime prevalence of about 13% in men and 21% in women (Blazer, Kessler, McGonagle & Swartz, 1994). The World Health Organization has predicted that depression will globally become the 2nd largest burden of disease by 2020, following cardiovascular conditions (Murray & Lopez, 1997). Individuals with depression experience a wide range of symptoms including a loss of interest or pleasure, feelings of sadness, guilt, low self-esteem, disturbances in sleep and...
EEG & QEEG: From ‘Endophenotypes’ to ‘Biomarkers’
[vc_row][vc_column][vc_column_text el_class="maintext"][WP-Coder id="1"] From ‘Endophenotypes’ to ‘Biomarkers’ The concept of endophenotypes has been described as early as in 1966 and originated from a review on geographical distribution in insects where a clear case was made for not only investigating the exophenotype (“…the obvious and the external…”) but also the endophenotype (“…the microscopic and internal”) (John & Lewis, 1966). This term was further adopted by Gottesman and Shields (1967; 1972) in their studies on schizophrenia as ‘biochemical test or microscopic examination’ (Gottesman & Gould, 2003). The idea behind an endophenotype is that it is the intermediary step between genotype and behavior...
rTMS: repetitive transcranial magnetic stimulation and depression
[vc_row][vc_column][vc_column_text el_class="maintext"] [WP-Coder id="1"] Repetitive Transcranial Magnetic Stimulation (rTMS) in Depression: Protocols, Mechanisms and New Developments Arns, M.1,2,3, Iseger, T.1,3, Spronk, D. B. 1, Brown, T.4& Fitzgerald, P. B.5 1 Research Institute Brainclinics, Nijmegen, The Netherlands 2 neuroCare Group, Munich, Germany 3 Dept. of Experimental Psychology, Utrecht University, Utrecht, The Netherlands 4 neuroCare Group, Melbourne, Australia 5 Epworth Healthcare and Monash Alfred Psychiatry Research Centre, Melbourne, Australia Updated and revised version of: Repetitive transcranial magnetic stimulation in depression: Protocols, mechanisms and new developments. In Neuromodulation and neurofeedback: Techniques and applications. Elsevier. Abstract This book chapter introduces and explains protocols, mechanisms...