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The Brainclinics Foundation

Applied Neuroscience from the clinic,to the clinic

Research Institute Brainclinics was founded in 2001 as an independent research institute and specializes in advancing our understanding of the brain; applied neuroscience to advance rTMS techniques, and ADHD and depression research. The results of our research are a valuable aid in the treatment and prevention of symptoms such as mood-, concentration-, impulse control-, and sleep problems, often seen in disorders such as depression, ADHD, and insomnia. The expertise extends to the development and application of brain stimulation techniques, such as rTMS for depression and OCD, TMS induced Heart-Brain Coupling and EEG based precision psychiatry and stratified psychiatry for Depression and ADHD.

Masterclass

Our TMS Masterclass & Certification course takes you from the basics of TMS and Brain Stimulation, to exciting new developments in this field with world renown speakers from all over the...

Resources

Get access to our Brainclinics resources, such as books, theses and the open access TDBRAIN EEG dataset with more than 1200 EEG’s and descriptive data.

Research

Read more about our scientific publications and articles over the years.

Citations

9996

Publications

255

Co-authors

765

News

We regularly post news on Linkedin. Please follow us on Linkedin to get the latest news in your Linkedin feed. 

24 October 2024
Where AI meets EEG biomarkers: Here we used AI/Deep-Learning trained to identify 'spindling excessive beta' activity, and could demonstrate this hypoarousal EEG signature is caused by sleep maintenance problems and is specifically linked to impulse control problems independent of DSM diagnosis. In addition, this signature was associated with ADHD diagnostic status in a sex-specific manner and predicted response to Sertraline in depression specif...
17 October 2024
Time to start with an EEG before TMS treatment! 18Hz and 20Hz TMS target a different MDD sub-population relative to 10Hz TMS, offering great potential to stratify patients based on individual alpha frequency using EEG. https://lnkd.in/ektK6QD9 This was a great collaboration, great thanks to BrainsWay and Abraham Zangen for sharing their dTMS 18Hz EEG data and Salience TMS Neuro Solutions, LLC, Jonathan Downar, Victoria Middleton for sharing th...
17 October 2024
Interessant 20 jarig jubileumcongres van NedKAD met veel interessante topics, van psychedelica, exposure therapie tot brain stimulation en onze bijdrage waarin we de vraag beantwoorden of we klaar zijn voor biomarkers in de klinische praktijk: Precisie Psychiatrie vs Stratified Psychiatrie.
07 October 2024
Screen use 2 hours before bedtime had no effect on total sleep duration, but it did delay sleep onset by an average of 10 minutes, with interactive screen use in bed being more harmful for sleep compared to passive screen use. With the growing prevalence of screen use among adolescents, especially before bedtime, its potential impact on sleep health has garnered increased attention. A recent study published in JAMA Pediatrics explored the associ...
07 October 2024
Net uit in TvP: De toepassing van rTMS bij dwangstoornissen in Nederland en België: consensusverklaring Bij dwangstoornissen (OCS) die niet voldoende reageren op gedragstherapie of medicatie was het enige (vergoede) alternatief diepe hersenstimulatie (DBS). In deze consensusverklaring adviseren we niet-invasieve hersenstimulatie (TMS) te overwegen voordat bij iemand DBS geïndiceerd is. https://lnkd.in/eEMRZfBh Congrats: Odile A. van den Heuvel...
07 August 2024
Just out in AJP: rTMS as a Next Step in Antidepressant Nonresponders: A Randomized Comparison With Current Antidepressant Treatment Approaches. TMS was 5.5X more likely to result in remission relative to the next medication step after 2 failed treatments (27 vs 5% remission). Why even consider a third medication step? Congrats Iris Dalhuisen, Philip van Eijndhoven, Indira Tendolkar and colleagues for a great study. https://lnkd.in/g_us64aQ
07 August 2024
June 25th Helena Voetterl succesfully defended her PhD titled: Biomarkers from Bench to Bedside: Realizing a future of EEG-Based Stratified Psychiatry. Congrats Helena Voetterl! In her PhD she developed and clinically validated an EEG biomarker - called Brainmarker-I - as a biomarker to stratify ADHD or Depressed patients between various evidence based treatments, resulting in higher remission rates. This has become a great piece of work, with ...
07 July 2024
About sleep, concentration and 'ADHD-like' symptoms...
07 July 2024
Join me in celebrating 100 years of EEG, please reshare! On July 6th, 1924 Hans Berger recorded the first EEG on a human, only published in 1929. This invention of the EEG has resulted in many clinical applications ranging from diagnosing epilepsy and sleep disorders to Brain Machine Interfaces (BMI/BCI), neurofeedback and EEG as the first clinically actionable biomarker in precision and stratified psychiatry. What's your favorite application ...
07 July 2024
Last week Hannah Meijs succesfully defended her PhD titled: Decoding Complexity: A data-driven approach to unraveling transdiagnostic markers in psychiatry. Congrats Hannah Meijs! This has become a great piece of work, probably including the largest amount of EEG data ever in a PhD, exceeding >7.5K unique EEG's and sophisticated analyses applied, including fICA LORETA and AI/Deep Learning. The PhD thesis is available for download here: https://l...

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