The Brainclinics Foundation

Scientific research

Brainclinics was founded in 2001 as an independent research institute by dr. Martijn Arns and specializes in advancing our understanding of the brain; applied neuroscience to advance rTMS techniques, and ADHD and depression research. The results of our research are a valuable aid in the treatment and prevention of symptoms such as mood-, concentration-, impulse control-, and sleep problems, often seen in disorders such as depression, ADHD, and insomnia.

Forward thinking

Over the last 20 years, Brainclinics has pioneered the application of neurofeedback in the treatment of ADHD and insomnia, was one of the first to recognize the importance of the circadian clock and sleep problems underlying many symptoms like impaired concentration and impulse control, specifically in ADHD, while also pioneering and refining magnetic brain stimulation (rTMS) in the treatment of depression and obsessive–compulsive disorder (OCD) and in 2017 invented Neuro-Cardiac-Guided TMS to more specifically target the Frontal-Vagal network in Depression. In 2019 the legal structure was changed, and the non-profit Brainclinics Foundation was established.


The Brainclinics Foundation’s primary mission is best summarized as: Applied Neuroscience from the clinic, to the clinic. Therefore, the two pillars of the foundation are formed by the independent Research Institute Brainclinics and Brainclinics Insights (the publishing division).

applied neuroscience

Personalized medicine

At Research Institute Brainclinics researchers have published over 170 scientific publications on these and related topics and continue to collaborate with researchers and universities around the world ranging from Australia, Germany, Belgium, the United States to Colombia. A key topic of our research revolves around ‘personalized medicine’, going beyond the traditional ‘diagnostic-thinking’ and focusing on individual differences that can help optimize and individualize treatment and prevent symptoms from occurring.

Brainclinics Insights: Publishing and interactive media

Brainclinics Insights is the publishing division of our foundation. Its mission is to make the knowledge, expertise and especially ‘Insights’ gained through our research, widely available through books, PhD theses and interactive media. As an example, you can here find our latest documentary series titled ‘Pioneers of the EEG’ as well as various books and PhD-theses’ that are also published in the Apple bookstore. If you want to keep up-to-date, also make sure to follow our informative Youtube channel.

To serve the goal of the Brainclinics Foundation, all proceeds are fully invested into Research Institute Brainclinics and Brainclinics Insights, which creates an unprecedented synergy between these divisions and makes it possible to perform research and share new future insights into applied neuroscience as well.

At the Brainclinics Foundation, it is all about the research and its application!


Our research has resulted in 4 patents and several spin-offs, such as Brainquiry, where the first ever wireless Bluetooth based EEG amplifier was developed in 2003 and the first wrist-worn heart-rate device in 2005 (nine years before Apple launched the Apple Watch with similar technology). Other spin-offs are Brainclinics Education, where specialistic applied neuroscience training courses were developed focused on rTMS, neurofeedback and QEEG, and Brainclinics Treatment, where our unequalled knowledge and expertise on personalized neuromodulation treatments are applied to benefit people worldwide. In 2015, Brainclinics Education and Brainclinics Treatment were acquired by the neuroCare Group, where courses are still taught by neuroCademy, and neuromodulation treatments that followed from Brainclinics Research are offered in >15 neuroCare clinics worldwide.


The most important pillar of our philosophy and mission is independence. Our non-profit foundation status ensures it is all about knowledge creation and content and our independence from companies and universities, but collaboration with companies and universitites ensures we conduct research independently and free of bias,  but is focused on clinical relevance, or as stated in our misison: Applied Neuroscience from the clinic, to the clinic!

[Public comment: A questionnaire to collect unintended effects of TMS] Dear All, we welcome public comment that will help in finalizing the manuscript.

Please send your comments to '' by Nov 6. The final version will be published afterward.

IPEG Virtual Meeting 27th-29th October: TWO DAYS LEFT TO SUBMIT YOUR ABSTRACT https://www.ipeg-society.org/meetings/
and automatically apply for the W.HERRMANN Grant (750 - 500 - 250€): https://www.ipeg-society.org/prizes/
Preliminary Program: https://www.ipeg-society.org/wp-content/uploads/2021/10/2021-Virtual-IPEG-Conference_Oct07_2021.pdf

Hot off the press, Investigating #EEG BIOMARKERS OF CLINICAL RESPONSE TO LF #rTMS in #depression https://www.sciencedirect.com/science/article/pii/S2666915321001761

Dear colleagues: we have several postdoctoral openings in my lab for several new multi-modal imaging studies focused on depression and anhedonia. Details at https://tinyurl.com/4syetw4x. Women and minorities underrepresented in neuroscience/medicine are encouraged to apply. Please RT

Today we are glad to share that a new project for our client Brainclinics Foundation has started!🤝The project is aimed at creating an environment, where the data acquisition, processing, and result visualization are streamlined into one environment. #digitalbiomarkers #Orikami

Just published: Evaluation of the URGOnight Tele-neurofeedback Device: An Open-label Feasibility Study with Follow-up
Effects of a home based SMR Neurofeedback device on sleep problems, with specific effect for learners.


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Evaluation of the URGOnight Tele-neurofeedback...

Applied Psychophysiology and Biofeedback - SMR neurofeedback shows potential as a therapeutic tool for reducing sleep ...


Those with obstructive sleep apnea who were treated with PAP had lower rates of Alzheimer's dementia, with the most adherent having the lowest dementia rates (Dunietz 2021). #OSA

Getting bright light in the day is as important as avoiding light at night. We looked at outdoor light exposure in >400,000 people - more light: better mood, less risk of depression, lower antidepressant use, better sleep. Get those free photons! 🌞https://doi.org/10.1016/j.jad.2021.08.056

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